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elegans of the glycerol-3-phosphate phosphatase PGPH-2, homologous to human candidate longevity gene PGP (Torres et al., 2021), which hydrolyzes glycerol-3-phosphate to decrease G3PS flux, extended nematode lifespan (Possik et al., 2023)

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Carnitine might be conditionally essential in individuals with such conditions because it may support acetylcholine synthesis and help remove toxic compounds to alleviate mitochondrial dysfunction associated with extensive degeneration of brain structures

10.1111/jfbc.13635 88 Nasiri-AmiriF.FaramarziM.OmidvarS.Alizadeh-NavaeiR

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