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Tirzepatide acts as a dual incretin receptor agonist, targeting both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors

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Table 1: Pre- and Post-Diagnosis Code GLP-1 RA Utilization Trend

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The key concern is that people who start GLP-1 medications may differ in important ways from people starting other diabetes drugs. People who are starting GLP-1s could be more motivated to change their behaviors, be more engaged with their health care or receive more intensive follow-up from clinicians, Alexander said

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