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Identification of a choroid plexus vascular barrier closing during intestinal inflammation

2012 Jan;16(1):75-86

In this study, administration of (Pro 3 )GIP or exendin(939)amide to ( ob / ob ) mice reduced meal-induced insulin release by 42% and 54%, respectively

The gut-brain axis needs time to respond to changes in GLP-1, and gradual titration keeps the process gentle

Some, like inulin and fructans (chicory root, Jerusalem artichokes, leeks, onions, asparagus) and GOS, are associated with higher Akkermansia levels in studies

Gradual dose escalation over several weeks allows your body to adapt to gastrointestinal side effects whilst optimising therapeutic response