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In the European market, probiotic ingredients are commonly found in pharmaceutical and nutraceutical products sold in pharmacies and supermarkets (282)

Therefore, a pan-coronavirus vaccine that is able to induce immunity targeting combinations of epitopes conserved across the whole coronavirus family should also protect against future variants and emerging viral species, in which these epitopes will likely be retained owing to functional constraints

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Rather, they fail within a complex, multicellular environment in which astrocytes, microglia, oligodendrocytes, vascular elements, and systemic immune components actively participate

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