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Both hormones matter, but GLP-1 is likely the primary driver with GIP providing substantial enhancement

Food intake To assess normal eating habits, instructions will be provided to record all food and beverages consumed on 2 working days and 1 weekend day in a 3-day food diary

This is the medication doing exactly what it should at this phase of treatment

However: Semaglutide: Patients may experience mild to moderate GI symptoms during the dose adjustment period

Blood glucose self-monitoring is necessary to adjust the dose of sulfonylurea and insulin particularly when Orsema is started and insulin is reduced

Consequently, insurance plans are unlikely to cover it unless patients are also diabetic