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Celebrity endorsements and social media visibility have normalized discussion of weight-loss drugs, reducing stigma that historically kept many people from pursuing pharmacologic treatment

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To minimise these effects, follow the prescribed dose titration schedule, eat smaller meals, avoid high-fat or spicy foods, and stay well-hydrated

Foods, Supplements and Substances to Avoid Alcohol may worsen gastrointestinal side effects and compound hypoglycaemia risk when retatrutide is used with insulin or sulfonylureas

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This pulsatile pattern is important for keeping receptor response and avoiding desensitization