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Preclinical and clinical Phase 2 trials have shown significant weight loss potential, with models reaching 24%+ reductions over a 48-week period

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Tirzepatide: In a clinical trial of people with type 2 diabetes, tirzepatide caused an average weight loss of 13%15% in 72 weeks

The normal bladder urothelium is highly impermeable to urinary solutes and irritants such as urea, ammonia, and potassium

doi: 10.3390/ijms19071906

SAHPRA has warned that Ozempic is registered for type 2 diabetes in adults and is not registered for weight loss, while Wegovy is the semaglutide product registered for weight management and Mounjaro is registered for type 2 diabetes