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It encourages the differentiation of macrophages into pro-fibrotic M2 phenotypes and an increase in extracellular matrix synthesis, which exacerbates renal fibrosis
After TGF signalling inhibition in the high-glucose group, -SMA expression was significantly reduced to an undetectable level (Fig
Oral supplementation with curcumin reduces OS generated by hyperthyroidism in rats, as shown by decreased LPx and protein carbonyl (PC) levels and increased SOD and CAT activities in tissues (34, 39, 49)
Este efecto de modulacin gnica se extiende a vas relacionadas con la respuesta a heridas, factores de crecimiento y mecanismos antifibrticos, lo que lo hace de creciente inters en los estudios de biologa regenerativa
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