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doi: 10.1016/j.nutres.2023.06.004 354 LuangphiphatWJamjureePChantarangkulCAmornariyakoolOTaweechotipatrM

Disruption to zinc availability can interfere with the enzymatic functions of HDACs and DNMTs, whose aberrant activity is a feature of epigenetic instability observed in developmental disorders and cancer 11,113,114,115

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10.1016/j.jdiacomp.2008.12.001 28 EvansJ

However, a significant proportion of patients continue to experience persistent symptoms despite achieving biochemical normalization (Biondi and Cooper, 2019)

Brand-name semaglutide plus separate b12 supplementation This represents the most straightforward alternative