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[17] This rash occurs in 3060% of people with SLE

For instance, C-terminal binding proteins 1 and 2 (CtBP1 and CtBP2) are known to interact with polycomb group complexes, including components such as REST/CoREST, HDAC1 and HDAC2, to mediate transcriptional repression

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The mole concern is clinically significant