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[5] For women taking tirzepatide with oral contraceptives, backup contraception may be advised during dose escalation due to potential reduced contraceptive exposure

Animal studies show foetal harm risks like growth restriction, and the drugs pass into breast milk, potentially affecting infants

For generic NDT drugs, foreign API use is even more probable

Levothyroxine is notoriously sensitive to anything that affects its absorption

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In short, the retatrutide clinical trials side effects safety profile remains GI-led, dose-related, and still incomplete at long duration