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The cancer chemotherapy drug methotrexate is used in Crohns patients that are steroid dependent or have not responded to glucocorticoids (Preiss 2010)

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Starting with a smaller serving and gradually increasing helps the body adjust comfortably

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If GLP-1 agonists can modulate this inflammation, thenat least theoreticallythey may help rebuild that system more effectively than anything weve tried so far

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