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5A) and found that TXNDC12 is involved in regulating glutathione metabolism

The addition of scores for the OCI-R obsessions subscale (Model 3) led to a statistically significant increase in ability to predict mean GIDYQ scores, F (1, 221) = 10.045, p = .002, and explained an additional 3.8% of the variance for mean GIDYQ scores

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In a 107-week carcinogenicity study in mice given 10, 60, or 200 mg/kg/day by oral gavage, an increased incidence of hepatocellular adenoma/carcinoma was observed at 200 mg/kg/day at systemic exposures 20 times the human exposure at 40 mg/day based on AUC

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