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This mechanism is distinct from how semaglutide (Wegovy) or tirzepatide (Zepbound) work

doi:10.1038/ejcn.2017.132 2 Sotgia S, Fois AG, Paliogiannis P, Carru C, Mangoni AA, Zinellu A

Upon LPS stimulation, macrophages upregulate serine synthesis and one-carbon metabolism, fueling epigenetic reprogramming that licenses IL-1 expression

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Low levels of BDNF were correlated with clinical severity of depression and mania (229, 230)

The formula is further enhanced with L-Carnitine a compound that improves the breakdown of starches and sugars and directly transports fatty acids into mitochondria for energy production and Vitamin B12, which manages carbohydrate metabolism and provides the neurological and energy production support that makes the whole formula more effective