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Animal studies have reported reduced offspring weight, but it is unclear whether this was due to the medication, maternal weight loss, or other factors

No currently approved drug comes close and there is no FDA-approved drug for MASLD, a condition affecting roughly 1 in 3 adults

PGC-1 co-activates the expression of nuclear respiratory factors 1 and 2 (NRF1 and NRF2) which further facilitates the transcription of genes associated with mitochondrial respiratory chain complexes

Anaphylaxis is life threatening and can be observed when there is shortness of breath and rapid swelling inside the mouth