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Large population studies show that adults with lower carotenoid consumption tend to report shorter sleep duration, suggesting that antioxidant status may influence healthy sleep patterns.34 A smaller randomized trial tested 12mg of astaxanthin daily for eight weeks and found improvements in several sleep parameters, along with reduced perceived stress compared to placebo.4 The authors proposed that astaxanthins antioxidant and neuroprotective activity including its ability to cross the bloodbrain barrier could help stabilize oxidative stress in brain regions involved in regulating sleep and mood
The sources of the oxidation stress could be environmental, intracellular or both
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Smoking and alcohol abuse might be reflected in reduced oral antioxidant capacity and in an increasing oxidative damage to cellular elements
GST also represents a scaffold protein to unite different members across signaling pathways
Additionally, neuron-TUNEL double staining showed that, compared with the control group, the proportion of TUNEL-positive neurons was significantly reduced in the T7-LNP@YHV984 group and the YHV984 group, with the lowest proportion in T7-LNP@YHV984 group (Fig
