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7 questions about B vitamin supplements October 10, 2023 If you follow professional or collegiate sports, youve probably heard at least a few athletes say they needed a B12 injection to boost their energy levels

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However, as with any supplement or treatment, there's potential for side effects, especially when B12 is given in very high doses

This complete absence of tolerability-driven discontinuations represents a remarkable safety finding and indicates that even when mild side effects occurred, they were sufficiently manageable that participants chose to continue treatment