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Small interfering RNA (si-GLP-1R) and siRNA-NC were purchased by RiboBio Co., Ltd

IL-17 in severe asthma

Increase water intake, eat more omega-3-rich foods (like walnuts and chia seeds), and use a thick, emollient-based moisturizer like shea butter

The two-layer membrane divides mitochondria into multiple cavities, which is known as mitochondrial compartmentalized structure. The mitochondrial structure mainly includes four distinct regions, including mitochondrial outer membrane (Outer Mitochondrial MembraneOMM), mitochondrial inner membrane (Inner Mitochondrial MembraneIMM), mitochondrial matrix, and intermembrane space (Kramer and Bressan, 2018)

Besides, to further confirm peroxynitrite-mediated activation of the NF-B pathway, we also measured the mRNA expression levels of known NF-B p65 target genes Bax , P53 , Bcl2 , and Bcl-xL

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