Consumers may think theyre getting a blockbuster GLP-1 drug like semaglutide the active ingredient in Ozempic and Wegovy or tirzepatide the active ingredient in Mounjaro and Zepbound in a format thats applied to the skin
For weight management (Wegovy / Mounjaro) EMA and Irish prescribing guidance currently restricts weight-loss GLP-1s to adults with (see our full eligibility guide): BMI 30 kg/m (obesity), or BMI 27 kg/m (overweight) plus at least one weight-related condition type 2 diabetes, hypertension, dyslipidaemia, obstructive sleep apnoea, or established cardiovascular disease You should also be willing to engage with lifestyle change (diet and physical activity) these medicines are an addition to, not a replacement for, behaviour change
A peptide
The trial tracked 17,604 adults ages 45 and older who had overweight or obesity and a cardiovascular condition, but no history of diabetes
There is no single dietary strategy that consistently prevents weight regain, but higher protein intake and attention to total energy intake are among the more evidence-based approaches
The peak concentrations after administration of intranasal spray were reached in 1.25 +/- 1.9 hours
