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Vigorous exercise could prove to be a health hazard since its known to trigger palpitations in some individuals

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Tirzepatide (Zepbound), a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, received FDA approval for chronic weight management in November 2023

Shaking introduces air bubbles and generates mechanical stress on the peptide molecules

However, it is important to note that these observations come exclusively from animal studies and that safety data in humans remain very limited