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Months 1-2: Weight Loss Accelerates What the trials documented: In the Phase 2 monotherapy trial, weight loss accrued steadily through the dosing period, building toward the 26-week endpoints of 9.1% at the 2.4 mg dose and 10.8% at 4.5 mg (Lau et al., 2021)

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(2018) demonstrated that CGA protects against acetaminophen (APAP)-induced liver toxicity by activating the ERK/Nrf2 (nuclear factor erythroid 2-related factor 2) antioxidative pathway in mice and hepatocytes