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En un ensayo clnico de fase 2 que evalu su uso en DM2, orforglipron redujo significativamente la HbA1c 2,10% en comparacin con 1,10% para dulaglutida y 0,43% para placebo34

Despite this flurry of announcements, industry leaders caution that expanded capacity will be gradual

Starting doses and escalation intervals differed across trial arms

American Academy of Dermatology meeting, February 2002

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10.1093/jnci/djv209 38 HottaN.AkanumaY.KawamoriR.MatsuokaK.OkaY.ShichiriM.et al (2006)