According to Michael Roberts, a representative for the site, patients' interest has shifted from casual browsing to more focused, research-driven questions
doi: 10.1038/nature08970 93 MattooS.YukM
Introduction Amyotrophic lateral sclerosis (ALS) is a complex multi-pathogenic neurodegenerative disorder primarily characterized by the loss of upper motor neurons in the brain and lower motor neurons in the spinal cord and the brain stem (Robberecht and Philips, 2013)
Among the biomarkers included in this study, PCA3 is the only one currently addressed in clinical practice guidelines at the level of early detection
Large-scale cohort analyses, such as the Framingham Heart Study, have reported that the myocardial mtDNA mutation burden in HF patients is approximately 3.5 times higher than in age-matched controls (Wei et al., 2014)
Importantly, 93% of the ATP necessary for normal brain functioning is supplied by mitochondria [20]