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That said, "generally safe" does not mean "universally safe for everyone in all circumstances." Individual reactions vary

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Gopal Grandhige, MD, FACS, Board-Certified Surgeon Last Reviewed: March 16, 2026 BPC-157 typically begins working within the first one to two weeks, with most patients noticing subtle improvements such as reduced soreness, better digestion, and decreased inflammation during this early phase

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