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The safety and effectiveness of TOUJEO have not been established in pediatric patients less than 6 years of age
However, the combination does increase hypoglycemia risk (especially with other glucose-lowering drugs), dehydration risk, and genital infection frequency
In Sexually transmitted infections treatment guidelines, 2021
The traditional approval also expands Filsparis indication, allowing for its use to slow the decline of kidney function in adult patients who are at risk of disease progressionwhile also removing a previous requirement of having a specific urinary protein level
In a similar model, intrathecal injections of exenatide inhibited thermal hyperalgesia and mechanical allodynia by enhancing spinal microglial expression of -endorphins, IL-10 and interleukin 4 (IL-4) [34, 35]
It's also being studied for fatty liver disease (NASH) and cardiovascular outcomes
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