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In contrast, inhaled anesthetics, such as isoflurane, have been associated (in both in vitro and experimental studies) with the activation of pathways that increase the expression of HIF-1 and HIF-2 and the promotion of anti-apoptotic properties, which may favor the invasion and dissemination of neoplastic cells [94]

Recent advances and future directions on the valorization of spent mushroom substrate (SMS): a review

Inside these tissues and cells, the 4-hydroxyproline-containing di- and tri-peptides are hydrolyzed by peptidases and/or prolidase to yield their constituent imino acids (4-hydroxyproline or proline) and glycine

However, significant uncertainties remain regarding dosing, standardization, and safety in long-term use

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