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There are some logistical hurdles to be overcome before this combination becomes a new standard of care

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As demonstrated by oxyntomodulin, a weak endogenous agonist for GLP-1 receptor and glucagon receptor, a strategy that simultaneously stimulates both GLP-1 and glucagon receptors can reduce food intake while increasing energy expenditure, synergistically enhancing weight loss [105-107]

Pharmacy-based reminder services, including text messages or automated calls when prescriptions are due for refill, provide an additional safety net

Under Canada's established generic pricing framework negotiated through the pan-Canadian Pharmaceutical Alliance (pCPA) the first generic to market typically enters at 7585% of the brand price

[11] However, any time you receive an injection, theres a very small risk of infection or allergic reaction