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They tend to become darker during periods of prolonged sun exposure (e.g., spring, summer) and fade during the autumn and winter months

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Li BU, Howard JC

GLP-1 specifically binds to the glucagon-like peptide-1 receptor (GLP-1R) in the body, directly stimulating the secretion of insulin by pancreatic -cells, promoting proliferation and differentiation, and inhibiting cell apoptosis, thereby exerting a glycemic lowering effect

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