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What the Research Actually Shows Published research on AOD-9604 describes: Modest body fat reduction in preclinical and early clinical settings Reduced triglycerides in some studies Minimal effect on IGF-1 confirmed across the clinical dataset Good tolerability adverse event rates in the phase 2 obesity trials were comparable to placebo Variable weight loss some patients respond better than others, consistent with many metabolic interventions The effect size in phase 2 obesity trials was modest typically in the range of a few pounds over the study period

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Sci Rep 11:113 Tornesello AL, Borrelli A, Buonaguro L, Buonaguro FM, Tornesello ML (2020) Antimicrobial peptides as anticancer agents: functional properties and biological activities

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Consequently, the concentration range of BHB may be a crucial factor influencing the alterations in renal fibrosis [102]

Kim HJ, Lee HJ, An SY, et al