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Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture

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FUNDING: This study was supported by the Key Project of Natural Science Foundation of Shandong Province (ZR2021ZD33)

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Exercise and cold exposure induce PGC-1 coactivators, amplifying ERR-dependent gene sets involved in fatty-acid uptake and -oxidation (for example, CPT1, MCAD), OXPHOS subunits, TCA cycle enzymes, and mitochondrial transcription factors (for example, TFAM)

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