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In cases of overdose, deferoxamine may be used as an antidote

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It could prove especially useful for clinicians treating infertility or amenorrhea in which direct stimulation is necessary

Second, to slow down the excretion out of the body and increase half-life in the blood, peptides can be fused with the Fc fragment of an antibody and protein scaffolds such as Staphylococcus A antigen (Affibody) or conjugated with polyethylene glycol and fatty acids to enables the peptides to bind to albumin

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Based on a flexible dosing protocol, Novo Nordisk indicated patients could modify their dosing throughout the trial