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Inhibition by p53 of GS-E transport by purified recombinant Rlip reconstituted in artificial liposomes supported the idea of mutually opposed functions of Rlip and p53, with the former acting to defend cells from apoptosis (in response to survivable stress) and the latter triggering suicide upon catastrophic stress
R., Petluru, P
Combining them, they form even greater protection against oxidative damage
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O prprio envelhecimento, doenas crnicas como diabetes, Parkinson, doenas hepticas, e outras que levam a nveis altos de stress oxidativo (excesso de radicais livres), uso excessivo de medicamentos, e altos nveis de xenobiticos, deficincias de nutrientes como glutamina, cisteina, glicina, selnio, e vitamina B2 levam a uma diminuio dos nveis de glutation redutase, enzima que sintetiza glutation no nosso organismo
doi: 10.1017/s0317167100013433
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