In SURMOUNT-3, when combined with intensive lifestyle intervention, average weight loss reached 26.6% the highest ever recorded for a drug trial
Hydration quick tips: Sip small amounts frequently rather than drinking large volumes at once
If you are doing well, the dose may be gradually increased in steps
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In this year-long study on weight loss, 2,037 overweight people were enrolled in a weight loss program

2.5mg dose side effects Common (30-40% of users): Mild nausea (first 2-3 days) Slight fatigue Reduced appetite Management : Eat smaller meals Avoid greasy foods Stay hydrated Ginger for nausea Duration : Usually resolves within 3-5 days 5mg dose side effects Common (40-50%): Moderate nausea (dose day + 1-2 days after) Constipation Mild headache Management : Anti-nausea medication (Zofran) if needed Increase fiber and water Walk after meals Electrolyte supplementation 7.5-10mg dose side effects Common (30-40%): Nausea (body adapted by now, less severe) Constipation (more common) Fatigue on injection day Management : Miralax or magnesium for constipation Inject evening instead of morning Meal timing strategies Lower fat intake 12.5-15mg dose side effects Common (20-30%): Similar to 10mg but slightly more intense GI slowdown Occasional reflux Management : Smaller, more frequent meals Avoid late-night eating Antacids if needed Consider staying at 10mg if intolerable Read our peptide safety guide for complete information
