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Interacciones de nutrientes Junto con varias vitaminas B (es decir, folato, vitamina B 12 , vitamina B 6 , y riboflavina), la colina es necesaria para el metabolismo de los cidos nucleicos y aminocidos, y para la generacin del donante universal del grupo metilo, la S-adenosilmetionina (SAM) (ver Figura 4 )