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It is known that kidneys are implicated in the removal of sRAGE and circulating AGEs and non-AGE ligands are present in CKD (128)

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CON and CAR decreased at the beginning to a significant minimum at 9 h pi and reached the baseline from 24 h pi until the end of the experiment

The most extensively documented involves upregulation of vascular endothelial growth factor (VEGF) and its receptor VEGFR2, promoting angiogenesis, the formation of new blood vessels, in injured tissue

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