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10.1046/j.1464-410x.2003.04224.x 21 Del CarloM.ColeA

Endothelial dysfunction is a condition that is marked by a decrease in endothelial-dependent vasodilation and an increase in endothelial inflammatory activity (3)

Perry Wilson wrote

This mechanism is the foundation of its documented ability to stimulate keratinocyte, endothelial cell, and stem/progenitor cell migration to sites of tissue damage in pre-clinical models

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Health risks aside, the Obesity Society (TOS) wasnt impressed with the ads optics