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GSK3B inhibition can induce the cysteine/glutamate transporter (xCT), through Phosphoinositide-3 kinases (PI3Ks), which imports cysteine and exports glutamate (an excitatory neurotransmitter), leading to an increase in cerebellar glutamate, which may play a role in epilepsy

Then I went once a month for an additional B12

V.et al (1999)

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Thioredoxin-like domain of human kappa class glutathione transferase reveals sequence homology and structure similarity to the theta class enzyme