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This switch is controlled by TRPM7-dependent Ca 2+ influx and requires actin polymerization, myosin recruitment and the formation of focal adhesions at the interface between the cell and the lateral channel walls

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Half-Life and Clearance Estimated Half-Life in Plasma Human pharmacokinetic data are unavailable, so half-life estimates stem from animal models

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the term 'triple incretin agonist' sometimes used in lay media is therefore imprecise