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Accordingly, we encourage the adoption of GLP-1RA plus SGLT2i combination therapy in patients with T2DM and established atherosclerotic cardiovascular disease (ASCVD) or multiple risk factors for ASCVD (i.e., age 55 years, overweight/obesity, dyslipidemia, hypertension, current tobacco use, left ventricular hypertrophy, and/or proteinuria)

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Participants receiving tirzepatide reached a 20.2% mean weight reduction at 72 weeks, whereas the semaglutide group lost 13.7%

Vitamin B12 Vitamin B12 supports red blood cell production, oxygen transport, energy metabolism, and nervous system health

However, from the available peptides that reached the level of clinical trials, the presented results are limited

Neurology 35:10571058