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The FDA warns that both CJC-1295 and ipamorelin carry risks of immunogenicity (triggering immune responses) and cardiovascular effects, including "increased heart rate and systemic vasodilatory reaction." One clinical trial of CJC-1295 was discontinued following a participants death, though the attending physician believed the event was "unrelated to treatment." Neither CJC-1295 nor ipamorelin is FDA-approved

C., Kimes, T

Rare but serious risks include pancreatitis

Tirzepatide, in particular, has shown dramatic reductions in hepatic fat fraction in clinical trials

Myo-inositol can be taken with or without food, but taking it after meals may reduce the chance of mild digestive discomfort for some individuals

And the growth hormone whose production they are alleged to increase is natural, making testing even harder