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These peptides have also been shown to exert anti-inflammatory properties, probably due to the prevention of bacterial translocation in the gut by the increase of TJ expression, the suppression of pro-inflammatory cytokines released by T cells, monocytes, and dendritic cells, and the prevention of macrophage activation and migration [28]

If approved, mazdutide could become a valuable treatment option for patients struggling with obesity complicated by type 2 diabetes, fatty liver, or metabolic syndrome