Wegovy, a medication that contains semaglutide, the same main ingredient as Ozempic, and Zepbound, a medication that contains tirzepatide, the same main ingredient as Mounjaro, are both FDA-approved for weight loss
Stool softeners such as docusate sodium (Colace) have minimal evidence supporting their efficacy as monotherapy and are generally not recommended alone for semaglutide-induced constipation
Never adjust doses or stop either medication without consulting your healthcare provider, as abrupt changes could affect treatment outcomes or cause withdrawal effects
When to Contact a Clinician While some period changes are nothing to worry about, others can be a sign of something more serious
Wegovy is approved for weight management at the higher 2.4 mg dose
The leading drugs in this category are Mounjaro (tirzepatide), Ozempic (semaglutide), and Rybelsus, which is the oral form of semaglutide