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For example, combinations of GLP-1/glucagon RA achieve more liver fat content reduction in people with MASLD compared to GLP-1 RA alone despite similar WL, likely due to the direct effect of glucagon on hepatic lipid oxidation [79]

Apoptosis is a caspase-dependent process activated by intrinsic (e.g., mitochondrial outer membrane permeabilization) or extrinsic (e.g., death receptor activation) stimuli