While IGF-1 plays a significant role in muscle growth, it does so by repairing tissue rather than increasing the overall protein content in muscle cells
Low levels may indicate little muscle mass, being elderly with a small frame and low muscle mass, or liver disease
This timing aligns with the bodys natural circadian rhythm, amplifying the massive surge of growth hormone that naturally occurs during the first cycle of deep, slow-wave sleep
Research protocols typically use 20-80 mcg daily via subcutaneous injection, cycled 4 weeks on, 4 weeks off
It is not intended for human or animal consumption, diagnosis, treatment or prevention of disease
In addition, chronological aging of the skin is influenced by genetics, metabolism, and hormonal, immunological, cardiovascular, gastrointestinal, psychogenic (involving stress or affective disorders), degenerative, or neoplastic disease [16,17,18]