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In short, despite some heterogeneity across the trials, GLP-1 receptor agonists were shown to reduce the hazard ratios [95%CI] for 3-MACE by 12 [618]%, cardiovascular death by 12 [419]%, myocardial infarction by 9 [016]% and stroke by 16 {724]%

Exendin-4 alleviates angiotensin II-induced senescence in vascular smooth muscle cells by inhibiting Rac1 activation via a cAMP/PKA-dependent pathway

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