while respiratory viral infections cause antioxidant enzyme expression/activity inhibition associated with reduced Nrf2 nuclear localization, decreased cellular levels and reduced ARE-dependent gene transcription (Komaravelli and Casola, 2014)
Environmental, lifestyle, and biological factors, including poor dietary habits via the gutbrain axis, may contribute to A accumulation and tau hyperphosphorylation
The depletion of GSH is a major factor in the pathology of COVID-19, particularly in association with more severe manifestations [48]
However, while both are essential for good health, what they do and how they do it differ significantly
The principal function of endogenous GSH is not to limit inflammation but to fine-tune the innate immune response to infection (Diotallevi et al., 2017
Gonzlez F, Rote NS, Minium J, Kirwan JP