Recommended Dosing Collagen: Most studies suggest a range of 10g to 20g per day for noticeable benefits in skin and joint health
10.1016/s0928-4257(97)89474-0 [DOI] [PubMed] [Google Scholar] Sikiric P., Seiwerth S., Grabarevic Z., Rucman R., Petek M., Jagic V., et al
PMA-induced expressions of ICAM-1 and MMP-9 at the RNA and protein level in a dose-dependent manner were also observed[218]
Id tried every diet and fasting method before, but nothing worked like this
Daily subcutaneous or intramuscular injection, ~200-300 mcg/day in standard use
Last reviewed: April 21, 2026 Updated with Phase 3 TRIUMPH-4 data Primary sources: NEJM, Eli Lilly, ClinicalTrials.gov Retatrutide is a triple agonist (GLP-1 + GIP + glucagon) currently in Phase 3 trials, showing stronger early weight loss data