glp-1 receptor agonists side effects : New England Journal of Medicine Considerations on Concurrent Glucagon-Like Peptide-1

Their ability to improve the gut lining, reduce inflammation, and promote overall recovery makes them worth exploring for many people struggling with chronic discomfort or inflammation

Abbreviations GLP1-RA: Glucagon like peptide-1 receptor agonist ASCVD: Atherosclerotic cardiovascular disease MACE: Major adverse cardiovascular events NNT: Numbers Needed to Treat MI: Myocardial Infarction CVD: Cardiovascular Disease SGLT2i: Sodium-glucose cotransporter-2 inhibitors LEADER: Liraglutide effect and action in diabetes: evaluation of cardiovascular outcome results T2DM: Type 2 Diabetes mellitus SELECT: Semaglutide effects on cardiovascular outcomes in people with overweight or obesity PREVENT: Predicting risk of cardiovascular disease events HF: Heart Failure PRISMA: Preferred reporting items for systematic review and meta-analyses RCT: Randomized controlled trial BMI: Body mass index RR: Risk ratio NNTB: Numbers needed to benefit NNTH: Number needed to harm ROB-2: Cochrane risk of bias 2 (ROB-2) tool FLOW: Evaluate renal function with semaglutide once weekly References Federation WH

This is not abstract chemistry

N., Pappin, D

Conclusions GLP-1RA medications have progressed beyond another tool for clinicians to manage type 2 diabetes, overweight, and obesity to therapies with robust cardiovascular outcomes

Diabetes 49, 424430 (2000)