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London: Blandford

doi: 10.1038/srep37744 23 HolstJJ

Neumann J, Hofmann B, Gergs U

[1] Mice [1] Male C57BL/6J mice (6-week-old

Long R3 IGF-1 is modified to help increase its potency and stability while still exerting anabolic effects similar to IGF-1 Long stands for the additional 13 amino acids added to the N-terminus of the peptide molecule, while R3 describes the replacement of the 3rd amino acid in the native hormone with arginine