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20,287 Deleting SLC39A14 in TFR knockout mice significantly reduces hepatic iron accumulation, and inhibits ferroptosis-mediated liver fibrosis in high iron-diet mice
Arachidonic acid-derived eicosanoids have a pro-inflammatory effect, but eicosanoids made from omega-3 fatty acids have an anti-inflammatory effect
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In addition, ZIP8-knockout mice display impaired iron recycling during inflammation, elevated splenic iron and reduced serum iron, highlighting ZIP8s role in systemic metal handling 175
PubMed 88
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